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Anaplastic Lymphoma Kinase Antibody (ALK)

Anaplastic Lymphoma Kinase Antibody (ALK) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAnaplastic Lymphoma Kinase (ALK)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC
Recommended dilutionsIHC (Paraffin): 1:50-1:100
NotesTitration of the ALK antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis ALK antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9UM73
PurityPurified
Description A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2, It appears to play an important role in the normal development and function of the nervous system, The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains, This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, a member of the insulin receptor subfamily of Tyr protein kinases, but not in normal lymphoid cells, is an orphan receptor, 5)(p23, Anaplastic lymphoma kinase, q35) that involves NPM1 and ALK
ImmunogenA portion of amino acids 14-43 from the human protein was used as the immunogen for this ALK antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ALK antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAnaplastic Lymphoma Kinase (ALK)
Short nameAnaplastic Lymphoma Kinase Antibody (ALK)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAnaplastic Lymphoma phosphorylation catalyst (Antibody to) (anaplastic lymphoma receptor tyrosine kinase)
Alternative techniqueantibodies
Alternative to gene target ALK and IDBG-42084 and ENSG00000171094 and 238, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, CD246 and NBLST3, Plasma membranes, this GO :0000187 and activation of MAPK activity and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004704 and NF-kappaB-inducing kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004704: NF-kappaB-inducing kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004704: NF-kappaB-inducing kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0038061 and NIK/NF-kappaB signaling and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0046777 and protein autophosphorylation and biological process this GO :0048666 and neuron development and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, anaplastic lymphoma receptor tyrosine kinase
Identity 427
Gene ALK
Long gene name anaplastic lymphoma receptor tyrosine kinase
Synonyms gene name anaplastic lymphoma kinase (Ki-1)
Synonyms CD246
Locus 2p23, 1 , 2-p23
Discovery year 1993-08-24
GenBank acession D45915
Entrez gene record 238
Pubmed identfication 8122112
RefSeq identity NM_004304
Classification CD molecules Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000152034
Locus Specific Databases LRG_488

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