Name : Angiotensin II Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7962189853
| Long name | Angiotensin II Primary Polyclonal Antibody |
| Also known as | Angiotensin II PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Angiotensin II |
| Specificity | The immunogen used generate this antibody is DRVYIHPF, corresponding to amino acids 34-41 of human Angiotensinogen, This is a highly specific antibody against Angiotensin II |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 34-41/485 |
| Subcellular location | Secreted |
| Source | MAP conjugated synthetic peptide derived from human Angiotensin II |
| Gene ID number | 183 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1, Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, Angiotensin-3: stimulates aldosterone release, Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets, Has vasodilator and antidiuretic effects, a potent regulator of blood pressure, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone, body fluid and electrolyte homeostasis, Essential component of the renin-angiotensin system (RAS) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ANG III, ANGT_HUMAN, ANHU, AT-2, AT-II, Ang II, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, Angiotensinogen serpin peptidase inhibitor, Pre angiotensinogen, SERPINA8, Serine or cysteine proteinase inhibitor, Serpin A8, antitrypsin, clade A member 8, Alpha 1 antiproteinase |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Angiotensin II |
| Short name | Angiotensin II Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Angiotensin II (Antibody to) |
| Alternative technique | antibodies |
| Identity | 338 |
| Gene | AGTR2 |
| Long gene name | angiotensin II receptor type 2 |
| Synonyms gene name | angiotensin receptor 2 |
| Synonyms | AT2 MRX88 |
| Locus | Xq23 |
| Discovery year | 1992-08-25 |
| GenBank acession | AY324607 |
| Entrez gene record | 186 |
| Pubmed identfication | 1550596 |
| RefSeq identity | NM_000686 |
| Classification | Angiotensin receptors X-linked mental retardation |
| Havana BLAST/BLAT | OTTHUMG00000022243 |
| Locus Specific Databases | Mental Retardation database |