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ANGPTL3 Antibody

ANGPTL3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameANGPTL3 Primary Polyclonal Antibody
Also known asANGPTL3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenANGPTL3
SpecificityThis is a highly specific antibody against ANGPTL3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range40-90/460
Subcellular locationSecreted
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3
Gene ID number27329
Swiss ProtQ9Y5C1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A deficiency of Angptl3 results in abnormally low lipid levels, Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3), Angptl3 may also play an important role in hyperlipidemia in diabetes, Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle, It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain, and a repression of the protein may be protective against atherosclerosis, Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ANG-5, ANGPT5, ANGPTL3, Angiopoietin-5, Angiopoietin-like protein 3, Angiopoietin-related protein 3, FHBL2, UNQ153/PRO179, ANL3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetANGPTL3
Short nameANGPTL3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameangiopoietin-like 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ANGPTL3 and IDBG-638594 and ENSBTAG00000021386 and 782603, ANGPTL3 and IDBG-99367 and ENSG00000132855 and 27329, Angptl3 and IDBG-166252 and ENSMUSG00000028553 and 30924, Extracellular, growth factor activity, this GO :0004857 and enzyme inhibitor activity and molecular function this GO :0004859 and phospholipase inhibitor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006071 and glycerol metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0009395 and phospholipid catabolic process and biological process this GO :0009725 and response to hormone and biological process this GO :0009986 and cell surface and cellular component this GO :0010519 and negative regulation of phospholipase activity and biological process this GO :0019915 and lipid storage and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050996 and positive regulation of lipid catabolic process and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0055090 and acylglycerol homeostasis and biological process this GO :0055091 and phospholipid homeostasis and biological process this GO :0070328 and triglyceride homeostasis and biological process, this GO :0004857: enzyme inhibitor activity, this GO :0004857: enzyme inhibitor activity and also this GO :0004859: phospholipase inhibitor activity and also this GO :0005178: integrin binding and also this GO :0008083: growth factor activity, this GO :0004859: phospholipase inhibitor activity, this GO :0005178: integrin binding, this GO :0008083: growth factor activity, angiopoietin-like 3
Identity 491
Gene ANGPTL3
Long gene name angiopoietin like 3
Synonyms gene ANGPT5
Synonyms gene name angiopoietin-like 3
Synonyms name angiopoietin 5
Locus 1p31, 3
Discovery year 2000-02-07
GenBank acession AF152562
Entrez gene record 27329
Pubmed identfication 10644446
RefSeq identity NM_014495
Classification Fibrinogen C domain containing Angiopoietin like
Havana BLAST/BLAT OTTHUMG00000009146

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