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ANGPTL3 Antibody, FITC Conjugated

ANGPTL3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, ANGPTL3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenANGPTL3
SpecificityThis is a highly specific antibody against ANGPTL3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range40-90/460
Subcellular locationSecreted
SourceKLH conjugated synthetic peptide derived from human ANG5/ANGPTL3
Gene ID number27329
Swiss ProtQ9Y5C1
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A deficiency of Angptl3 results in abnormally low lipid levels, Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3), Angptl3 may also play an important role in hyperlipidemia in diabetes, Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle, It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain, and a repression of the protein may be protective against atherosclerosis, Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetANGPTL3 Conjugated
Short name FITC Conjugated, ANGPTL3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, angiopoietin-like 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ANGPTL3 and IDBG-638594 and ENSBTAG00000021386 and 782603, ANGPTL3 and IDBG-99367 and ENSG00000132855 and 27329, Angptl3 and IDBG-166252 and ENSMUSG00000028553 and 30924, Extracellular, growth factor activity, this GO :0004857 and enzyme inhibitor activity and molecular function this GO :0004859 and phospholipase inhibitor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006071 and glycerol metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0009395 and phospholipid catabolic process and biological process this GO :0009725 and response to hormone and biological process this GO :0009986 and cell surface and cellular component this GO :0010519 and negative regulation of phospholipase activity and biological process this GO :0019915 and lipid storage and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050996 and positive regulation of lipid catabolic process and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0055090 and acylglycerol homeostasis and biological process this GO :0055091 and phospholipid homeostasis and biological process this GO :0070328 and triglyceride homeostasis and biological process, this GO :0004857: enzyme inhibitor activity, this GO :0004857: enzyme inhibitor activity and also this GO :0004859: phospholipase inhibitor activity and also this GO :0005178: integrin binding and also this GO :0008083: growth factor activity, this GO :0004859: phospholipase inhibitor activity, this GO :0005178: integrin binding, this GO :0008083: growth factor activity, angiopoietin-like 3
Identity 491
Gene ANGPTL3
Long gene name angiopoietin like 3
Synonyms gene ANGPT5
Synonyms gene name angiopoietin-like 3
Synonyms name angiopoietin 5
Locus 1p31, 3
Discovery year 2000-02-07
GenBank acession AF152562
Entrez gene record 27329
Pubmed identfication 10644446
RefSeq identity NM_014495
Classification Fibrinogen C domain containing Angiopoietin like
Havana BLAST/BLAT OTTHUMG00000009146

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