Name : Anti-5-Lipoxygenase(Ser271), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN5366545568
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | 5-Lipoxygenase Ser271 |
| Specificity | This antibody reacts specifically with 5-Lipoxygenase(Ser271) |
| Modification | Phosphorylation |
| Modification site | Ser271 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from rat 5-Lipoxygenase around the phosphorylation site of Ser271 |
| Gene ID | 240 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Alternatively spliced transcript variants have been observed, Leukotrienes are important mediators of a number of inflammatory and allergic conditions, Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers, The encoded protein, and further to the allylic epoxide 5(S)-trans-7, but their full-length nature has not been determined, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8, which is expressed specifically in bone marrow-derived cells, 11, 14-cis-eicosatetraenoic acid, 14-cis-eicosatetrenoic acid (leukotriene A4), 9-trans-11, This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | 5 LO, 5LPG, ALOX 5, ALOX5, Arachidonate 5 lipoxygenase, Arachidonic acid 5 lipoxygenase, LOG 5, LOG5, LOX5_HUMAN, Leukotriene A4 synthase, MGC163204, 5-lipoxygenase |
| Also known as | 5-Lipoxygenase(Ser271) Antibody |
| Other name | Anti-5-Lipoxygenase(Ser271) |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | 5-Lipoxygenase(Ser271) |
| Short name | Anti-5-Lipoxygenase(Ser271) Fluor 594 |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-5-Lipoxygenase(Ser271) |