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Anti-A Raf (Tyr301 + Tyr302), ALEXA Fluor 594

Anti-A Raf (Tyr301 + Tyr302), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideA Raf Tyr301 + Tyr302
SpecificityThis antibody reacts specifically with A Raf (Tyr301 + Tyr302)
ModificationPhosphorylation
Modification siteTyr301 + Tyr302
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synstic phosphopeptide derived from human A Raf around the phosphorylation site of Tyr301/302 [G(p-Y)(p-Y)WE]
Gene ID369
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 14-3-3 is also known to be an activator of RAFs, A RAF is expressed at a very high concentration in urogenital and kidney tissues, Activated RAF directly phosphorylates and activates MEK, RAF 1 and B RAF, RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain, These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway, This domain is conserved in A RAF and B RAF, The RAF family of signaling proteins has three isoforms: A RAF
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms A Raf proto oncogene serine/threonine protein kinase, A raf 1, ARAF, ARAF 1, ARAF1, ARAF_HUMAN, ARaf proto oncogene serine/threonine protein kinase, Oncogene Araf1, Oncogene PKS2, PKS, PKS 2, PKS2, Proto oncogene Pks, RAFA 1, RAFA1, Ras binding protein DA Raf, p-A RAF phospho Y301 + Y302, v raf murine sarcoma 3611 viral oncogene homolog, v raf murine sarcoma 3611 viral oncogene homolog 1, v raf oncogene homolog 1 murine sarcoma 3611 virus, A RAF phospho Y301 + Y302
Also known asA Raf (Tyr301 + Tyr302) Antibody
Other nameAnti-A Raf (Tyr301 + Tyr302)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetA Raf (Tyr301 + Tyr302)
Short nameAnti-A Raf (Tyr301 + Tyr302) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-A Raf (Tyr301 and Tyr302)

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