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Anti-ABCD4 (Polyclonal), ALEXA Fluor 594

Anti-ABCD4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideABCD4
SpecificityThis antibody reacts specifically with ABCD4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ABCD4
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A mutation in the ABCD1 gene causes X-linked adreno-leukodystrophy (X-ALD), ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol, ABCD1 localizes to peroxisomes, ABCD1-4 that are known to be present in the human peroxisome membrane, ABCD2 in mouse is expressed at high levels in the brain and adrenal organs, ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors, All four proteins are ABC half-transporters, PMP22 and ABCD3, The peroxisomal membrane comprises two quantitatively major proteins, a peroxisomal disorder which affects lipid storage, which are adversely affected in X-ALD, which dimerize to form an active transporter, The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PMP69 P70R EST352188
Also known asABCD4 Polyclonal Antibody
Other nameAnti-ABCD4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetABCD4
Short nameAnti-ABCD4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, member 4 (polyclonal), sub-family D (ALD), antibody to-adenosine triphosphate-binding cassette
Alternative techniquepolyclonals
Alternative to gene target ABC41 and EST352188 and MAHCJ and P70R and P79R and PMP69 and PXMP1L, ABCD4 and IDBG-11957 and ENSG00000119688 and 5826, ABCD4 and IDBG-646851 and ENSBTAG00000014633 and 528646, ATPase activity, Abcd4 and IDBG-156897 and ENSMUSG00000021240 and 19300, Plasma membranes, coupled to transmembrane movement of substances, coupled to transmembrane movement of substances, coupled to transmembrane movement of substances and molecular function this GO :0043190 and ATP-binding cassette (ABC) transporter complex and cellular component this GO :0055085 and transmembrane transport and biological process, member 4, sub-family D (ALD), this GO :0005524 and ATP binding and molecular function this GO :0005777 and peroxisome and cellular component this GO :0005778 and peroxisomal membrane and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006810 and transport and biological process this GO :0009235 and cobalamin metabolic process and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016887 and ATPase activity and molecular function this GO :0042626 and ATPase activity, this GO :0005524: ATP binding, this GO :0005524: ATP binding and also this GO :0016887: ATPase activity and also this GO :0042626: ATPase activity, this GO :0016887: ATPase activity, this GO :0042626: ATPase activity, ATP-binding cassette
Identity 68
Gene ABCD4
Long gene name ATP binding cassette subfamily D member 4
Synonyms gene PXMP1L
Synonyms gene name ATP-binding cassette, member 4 , sub-family D (ALD)
Locus 14q24, 3
Discovery year 1997-10-27
GenBank acession AF009746
Entrez gene record 5826
Pubmed identfication 9266848 9302272
RefSeq identity NM_005050
Classification ATP binding cassette subfamily D
Havana BLAST/BLAT OTTHUMG00000171207

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