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Anti-Aconitase 1 (Polyclonal), ALEXA Fluor 594

Anti-Aconitase 1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAconitase 1
SpecificityThis antibody reacts specifically with Aconitase 1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Aconitase 1/IRP-1
Gene ID48
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells, IRPs respond to stress mediators, Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins, They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs), also known as iron responsive element-binding protein-1 and -2 (IREâ, cytokines and hydrogen peroxide, including nitrogen monoxide, iron concentration and signaling factors, iron regulatory protein-1 and -2 (IRP-1 and -2), &euro, &ldquo, BP-1 and -2) or aconitase 1 and 2, Iron metabolism is essential for sustaining mammalian homeostasis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms IRP1 IREBP
Also known asAconitase 1 Polyclonal Antibody
Other nameAnti-Aconitase 1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAconitase 1
Short nameAnti-Aconitase 1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Aconitase 1 (polyclonal)
Alternative techniquepolyclonals
Identity 117
Gene ACO1
Long gene name aconitase 1
Synonyms gene IREB1
Synonyms gene name aconitase 1, soluble
Synonyms name aconitate hydratase, cytoplasmic soluble aconitase cytosplasmic aconitase
Locus 9p21, 1
Discovery year 1989-01-01
GenBank acession M58510
Entrez gene record 48
Pubmed identfication 2172968 2771641
RefSeq identity NM_002197
Havana BLAST/BLAT OTTHUMG00000019740

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