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Anti-ADAM13 (Polyclonal), ALEXA Fluor 594

Anti-ADAM13 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideADAM13
SpecificityThis antibody reacts specifically with ADAM13
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from Xenopus laevis ADAM13
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesOther Species
Cross Reactive Species detailsXenopus laevis
Background information A member of the metalloproteinase family containing disintegrin like domains (ADAMs) the functions of ADAM13 are still poorly understood, ADAM13 contains a putative furin cleavage site, ADAM13 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, ADAM13 has been shown to be proteolytically active, ADAM13 is also shed from cells in culture, ADAM13 may also act as a cell attachment molecule, ADAM13 may regulate cellular signaling via Src and Src tyrosine kinase, ADAM13 was also found in liver, EFG like, It is still unclear if any of these ADAMs are species orthologs of Xenopus ADAM13, Predicted mass is 99, Shed ADAM13 is a 52 kD protein, The full length Xenopus ADAM13 sequence codes for a 914 amino acid protein, Xenopus ADAM13 has greatest homology with human ADAM 33 (51% identical), and 97 kD processed forms, and can form complexes with a2 macroglobulin, and intestines from adult Xenopus, and is 46% identical with human or mouse ADAM12 or ADAM19, and is released into the culture media, as well as disintegrin, but glycosylation and cyteine rich regions give Xenopus ADAM13 an apparent MW of 120 kD unprocessed, but there are significant differences between the related sequences, by binding integrins through the cysteine rich domain amoung many other roles, cleaved aminoterminal from the transmembrane domain, cleaving fibronectin after binding it to the EGF like domain, cysteine rich, heart, in developing Xenopus embryos, on reduced SDS PAGE gels, suggesting it is a competent protease, suggesting that ADAM13 may be a unique protein, suggesting that a prohormone convertase cleaves the propeptide domain away from the catalytic domain, transmembrane and Cytoplasmic domains, 749 kD, ADAM13 was first described as a protein expressed in somatic mesoderm and neural crest cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
SynonymsNULL
Also known asADAM13 Polyclonal Antibody
Other nameAnti-ADAM13 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetADAM13
Short nameAnti-ADAM13 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ADAM13 (polyclonal)
Alternative techniquepolyclonals

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