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Anti-ADAMTS4 (Polyclonal), ALEXA Fluor 594

Anti-ADAMTS4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideADAMTS4
Specificity based upon a 73% sequence similarity in the epitope region, there is a chance that this antibody may have a cross-reactivity with this protein, ADAMTS4, Due to the similarity this protein to ADAMTS1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Secreted, Extracellular
Antigen SourceKLH conjugated synthetic peptide derived from human ADAMTS4
Gene ID9507
Swiss ProtO75173
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Cleaves aggrecan at the '392-Glu-|-Ala-393' site, Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease, May play an important role in the destruction of aggrecan in arthritic diseases, a cartilage proteoglycan, and may be involved in its turnover, Cleaves aggrecan
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0688 ADAMTS-2 ADMP-1
Also known asADAMTS4 Polyclonal Antibody
Other nameAnti-ADAMTS4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetADAMTS4
Short nameAnti-ADAMTS4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ADAMTS4 (polyclonal)
Alternative techniquepolyclonals
Identity 220
Gene ADAMTS4
Long gene name ADAM metallopeptidase with thrombospondin type 1 motif 4
Synonyms gene name 4 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif
Locus 1q23, 3
Discovery year 1999-04-15
GenBank acession AB014588
Entrez gene record 9507
Pubmed identfication 10094461
RefSeq identity NM_005099
Classification ADAM metallopeptidases with thrombospondin type 1 motif
Havana BLAST/BLAT OTTHUMG00000034349

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