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Anti-ADAMTS8 (Polyclonal), ALEXA Fluor 594

Anti-ADAMTS8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideADAMTS8
SpecificityThis antibody reacts specifically with ADAMTS8
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ADAMTS8
Gene ID11095
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 2, 3 and 4, ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, ADAMTS8 has a propeptide domain, ADAMTS8 is inhibited by the endogenous MMP inhibitors, In addition to the metalloprotease domain, TIMP1, The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, They have been demonstrated to have important roles in connective tissue organization, a Prohormone Convertase (PC, a cysteine rich domain and thrombospondin 1 like domains, and has been shown to be proteolytically active on a range of substrates, angiogenesis and cell migration, arthritis, but most efficiently by TIMP3, coagulation, furin) cleavage site, inflammation, the function of ADAMTS8 is still poorly understood, versican and brevican, A member of the metalloproteinase family containing disintegrin like domains (ADAMs), ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms METH2 FLJ41712 ADAM-TS8
Also known asADAMTS8 Polyclonal Antibody
Other nameAnti-ADAMTS8 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetADAMTS8
Short nameAnti-ADAMTS8 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name 8 (polyclonal), ALEXA Fluor 594, antibody to-ADAM metallopeptidase including thrombospondin classification 1 motif
Alternative techniquepolyclonals
Alternative to gene target 8, ADAM-TS8 and METH2, ADAMTS8 and IDBG-642991 and ENSBTAG00000010411 and 512544, ADAMTS8 and IDBG-76259 and ENSG00000134917 and 11095, Adamts8 and IDBG-146397 and ENSMUSG00000031994 and 30806, Extracellular, low affinity phosphate transmembrane transporter activity, this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0006508 and proteolysis and biological process this GO :0008201 and heparin binding and molecular function this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009673 and low affinity phosphate transmembrane transporter activity and molecular function this GO :0031012 and extracellular matrix and cellular component this GO :0035435 and phosphate ion transmembrane transport and biological process, this GO :0004222: metalloendopeptidase activity, this GO :0004222: metalloendopeptidase activity and also this GO :0005178: integrin binding and also this GO :0008201: heparin binding and also this GO :0008237: metallopeptidase activity and also this GO :0008270: zinc ion binding and also this GO :0009673: low affinity phosphate transmembrane transporter activity, this GO :0005178: integrin binding, this GO :0008201: heparin binding, this GO :0008237: metallopeptidase activity, this GO :0008270: zinc ion binding, this GO :0009673: low affinity phosphate transmembrane transporter activity, ADAM metallopeptidase with thrombospondin type 1 motif
Identity 224
Gene ADAMTS8
Long gene name ADAM metallopeptidase with thrombospondin type 1 motif 8
Synonyms gene name 8 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif
Locus 11q24, 3
Discovery year 1999-08-23
GenBank acession AF060153
Entrez gene record 11095
Pubmed identfication 10438512
RefSeq identity NM_007037
Classification ADAM metallopeptidases with thrombospondin type 1 motif
Havana BLAST/BLAT OTTHUMG00000165656

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