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Anti-ADAMTSL2 (Polyclonal), ALEXA Fluor 594

Anti-ADAMTSL2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideADAMTSL2
SpecificityThis antibody reacts specifically with ADAMTSL2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ADAMTSL2
Gene ID9719
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ADAMTS protein family members contain an amino-terminal propeptide domain, ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, ADAMTS-L2 interacts with LTBP-1, In individuals affected with geleophysic dysplasia, Interestingly, Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex, a metalloproteinase domain, an autosomal recessive disorder characterized by cardiac vavular anomalies, including arthritis and cancer, kidney and liver, short stature, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts, thick skin and brachydactyly, ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0605
Also known asADAMTSL2 Polyclonal Antibody
Other nameAnti-ADAMTSL2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetADAMTSL2
Short nameAnti-ADAMTSL2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ADAMTSL2 (polyclonal)
Alternative techniquepolyclonals
Identity 14631
Gene ADAMTSL2
Long gene name ADAMTS like 2
Locus 9q34, 2
Discovery year 2005-01-12
GenBank acession AB011177
Entrez gene record 9719
Pubmed identfication 9628581 14667842
RefSeq identity NM_014694
Classification ADAMTS like
Havana BLAST/BLAT OTTHUMG00000131706

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