Name : Anti-ADAMTSL2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6091304846
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ADAMTSL2 |
| Specificity | This antibody reacts specifically with ADAMTSL2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human ADAMTSL2 |
| Gene ID | 9719 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | ADAMTS protein family members contain an amino-terminal propeptide domain, ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, ADAMTS-L2 interacts with LTBP-1, In individuals affected with geleophysic dysplasia, Interestingly, Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex, a metalloproteinase domain, an autosomal recessive disorder characterized by cardiac vavular anomalies, including arthritis and cancer, kidney and liver, short stature, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts, thick skin and brachydactyly, ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA0605 |
| Also known as | ADAMTSL2 Polyclonal Antibody |
| Other name | Anti-ADAMTSL2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ADAMTSL2 |
| Short name | Anti-ADAMTSL2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-ADAMTSL2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 14631 |
| Gene | ADAMTSL2 |
| Long gene name | ADAMTS like 2 |
| Locus | 9q34, 2 |
| Discovery year | 2005-01-12 |
| GenBank acession | AB011177 |
| Entrez gene record | 9719 |
| Pubmed identfication | 9628581 14667842 |
| RefSeq identity | NM_014694 |
| Classification | ADAMTS like |
| Havana BLAST/BLAT | OTTHUMG00000131706 |