Name : anti-ADRA2B Antibody
Supplier : PROSCIENCE
Price :180
SKU : GEN5999572406
| Gene info | <, A polymorphic variant of the a, For antagonists, The rank order of potency for agonists of this receptor is clonidine >, These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system, They include 3 highly homologous subtypes: a, This protein contains no introns in either its coding or untranslated sequences, This protein is the a, a, a guanine nucleotide exchange protein that functions in regulation of translation, alprenolol >, and a, chlorpromazine >, dopamine >, epinephrine = oxymetazoline >, mianserine >, norepinephrine >, p-synephrine / p-octopamine, p-tyramine = phenylephrine >, phentolamine >, pindolol, prazosin >, propanolol >, serotonin >, spiperone >, the rank order is yohimbine >, this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization, which lacks 3 glutamic acids from a glutamic acid repeat element, which was observed to associate with eIF-2B, <, -2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins, -2-adrenergic receptors are members of the G protein-coupled receptor superfamily, /b>, /b>, 2A, 2B, 2B subtype, 2B subtype, 2C, : a, : a, FUNCTION<, SUMMARY<, b>, b> |
| Gene names | ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, Alpha-2 adrenergic receptor subtype C2, Alpha-2B adrenergic receptor, Alpha-2B adrenoceptor, Alpha-2B adrenoreceptor, Alpha2B adrenergic receptor, alpha-2BAR, ADRA2L1 |
| Antibodie's label | unlabelled serum |
| Purity | Immunoaffinity Purified |
| Ab raised in | Chicken |
| Type | Polyclonal |
| Antigen | 200-299 |
| Immuno application | Western Blot |
| Antibody advice | -2B adrenergic receptor antibody can be used for the detection of a, -2B adrenergic receptor by Western Blot, a |
| Suspention, pH, azide | No preservatives added, Phosphate-Buffered Saline |
| Keep at | Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, ADRA2B antibody can be stored at 4 grades C for short term (weeks) |
| Works with | Human |
| Omim nr | 4501965 |
| Ncbi nr | 1, NP_000673 |
| KDa | 50 kDa (calculated) |
| Vial with antibody | in solution |
| Quantity per ml | 1 mg/mL |
| NCBI GENE nr | 151 |
| GENE symbol | ADRA2B |
| Antigene name | adrenoceptor alpha 2B |
| Source | Homo sapiens |
| Protein nr | P18089 |
| Description | Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target | ADRA2B |
| Short name | anti-ADRA2B Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name | antibody to-ADRA2B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 282 |
| Gene | ADRA2B |
| Long gene name | adrenoceptor alpha 2B |
| Synonyms gene | ADRA2L1 ADRA2RL1 |
| Synonyms gene name | adrenergic, alpha-2B-, receptor |
| Synonyms | ADRARL1 |
| Locus | 2q11, 2 |
| Discovery year | 1990-09-10 |
| GenBank acession | M34041 |
| Entrez gene record | 151 |
| Pubmed identfication | 2164221 |
| Classification | Adrenoceptors |
| Havana BLAST/BLAT | OTTHUMG00000188276 |