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Anti-Aggrecan (Polyclonal), ALEXA Fluor 594

Anti-Aggrecan (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAggrecan
SpecificityThis antibody reacts specifically with Aggrecan
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from Human Aggrecan
Gene IDN/A
Swiss ProtP16112
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Aggrecan accounts for the compressive stiffness and resilience of the hyaline cartilage, Aggrecan in cartilage forms aggregates with hyaluronan and link protein, Aggrecan is a complex multidomain macromolecule that undergoes extensive processing and post-translational modification, Aggrecan is a member of the chondroitin sulphate proteoglycan family, Brevican is a brain proteoglycan of the aggrecan/versican/neurocan family, In the adult brain, Many forms of inflammatory arthritis are shown to be accompanied with aggrecan degradation and loss from the cartilage, aggrecan, embedded in a collagen network, is the predominant proteoglycan present in cartilage, neurocan and brevican, the brevican core protein undergoes proteolytic cleavage and exists as a full-length form a carboxy-terminal fragment and an amino-terminal fragment, which also includes versican/PG-M, The large chondroitin sulfate proteoglycan
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CSPGCP ACAN
Also known asAggrecan Polyclonal Antibody
Other nameAnti-Aggrecan Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAggrecan
Short nameAnti-Aggrecan (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Aggrecan (polyclonal)
Alternative techniquepolyclonals
Identity 7338
Gene MSK16
Long gene name aggrecan
Synonyms gene CSPG1 AGC1
Synonyms gene name chondroitin sulfate proteoglycan 1 aggrecan 1
Synonyms name aggrecan proteoglycan
Locus 15q26, 1
Discovery year 1992-06-17
GenBank acession M55172
Entrez gene record 176
Pubmed identfication 1985970
RefSeq identity NM_001135
Classification Sushi domain containing Hyalectan proteoglycans V-set domain containing C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000171989

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