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Anti-AIF (Polyclonal), ALEXA Fluor 594

Anti-AIF (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismMouse (Mus musculus)
Target Protein/PeptideAIF
SpecificityThis antibody reacts specifically with AIF
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human AIF
Gene ID9131
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Rabbit, Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A related pseudogene has been identified on chromosome 10, Alternative splicing results in multiple transcript variants, In addition, Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation, May 2010], Mutations in this gene cause combined oxidative phosphorylation deficiency 6, [provided by RefSeq, and it is found in the mitochondrial intermembrane space in healthy cells, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9, which results in a severe mitochondrial encephalomyopathy, This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms AIF CMTX4
Also known asAIF Polyclonal Antibody
Other nameAnti-AIF Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAIF
Short nameAnti-AIF (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-AIF (polyclonal)
Alternative techniquepolyclonals
Identity 8768
Gene AIFM1
Long gene name apoptosis inducing factor mitochondria associated 1
Synonyms gene PDCD8 NAMSD
Synonyms gene name 1 apoptosis inducing factor, axonal, mitochondria associated 1 , mitochondrion-associated, motor-sensory with deafness and mental retardation (Cowchock syndrome) apoptosis-inducing factor, programmed cell death 8 (apoptosis-inducing factor) neuropathy
Locus Xq26, 1
Discovery year 1999-05-28
GenBank acession AF100928
Entrez gene record 9131
Pubmed identfication 9989411 23217327
Havana BLAST/BLAT OTTHUMG00000022392
Locus Specific Databases Mental Retardation database

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