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Anti-AIP1 (Polyclonal), ALEXA Fluor 594

Anti-AIP1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAIP1
SpecificityThis antibody reacts specifically with AIP1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human AIP1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukemia (AML), Expressed at low levels in prostate tissue, also known as DAB2IP (DAB2 interacting protein), disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, implicating a role for AIP1 fusion proteins in tumorigenesis, is a 1, one PH domain and one C2 domain, suggesting a role in tumor suppression, thereby allowing free ASK 1 to function within the cell, via this interaction, 189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, AIP1 (ASK-interacting protein 1)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Alix AIP1 Hp95
Also known asAIP1 Polyclonal Antibody
Other nameAnti-AIP1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAIP1
Short nameAnti-AIP1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-AIP1 (polyclonal)
Alternative techniquepolyclonals
Identity 8766
Gene PDCD6IP
Long gene name programmed cell death 6 interacting protein
Synonyms gene name programmed cell death 6-interacting protein
Synonyms name ALG-2 interacting protein X
Locus 3p22, 3
Discovery year 1999-12-10
GenBank acession BC020066
Entrez gene record 10015
Pubmed identfication 9880530
Havana BLAST/BLAT OTTHUMG00000130751

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