Name : Anti-AIPL1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8529464512
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | AIPL1 |
| Specificity | This antibody reacts specifically with AIPL1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus, Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human AIPL1 |
| Gene ID | 23746 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | AIPL1 is crucial for protein folding and stabilization, AIPL1 is expressed in both developing cone and rod photoreceptors, Defects in the gene encoding for AIPL1 can cause Leber congenital amaurosis type IV, In the retina, It localizes to the nucleus or cytoplasm and is highly expressed in the pineal gland and the retina, an early-onset, aryl hydrocarbon receptor interacting protein-like 1 (AIPL1), as well as for protein trafficking, but it is restricted to rod photoreceptors in the adult human retina, inherited autosomal recessive disorder that results in childhood blindness, interacts with the cell cycle regulator protein NUB1, The inherited blindness associated protein |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | AIPL1 Polyclonal Antibody |
| Other name | Anti-AIPL1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | AIPL1 |
| Short name | Anti-AIPL1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-aryl hydrocarbon receptor interacting protein-like 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | AIPL1 and IDBG-21975 and ENSG00000129221 and 23746, AIPL1 and IDBG-633925 and ENSBTAG00000008318 and 281609, AIPL2 and LCA4, Aipl1 and IDBG-196135 and ENSMUSG00000040554 and 114230, nuclei, this GO :0001895 and retina homeostasis and biological process this GO :0001917 and photoreceptor inner segment and cellular component this GO :0001918 and farnesylated protein binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006457 and protein folding and biological process this GO :0007601 and visual perception and biological process this GO :0007603 and phototransduction, this GO :0001918: farnesylated protein binding, this GO :0001918: farnesylated protein binding and also this GO :0005515: protein binding and also this GO :0051082: unfolded protein binding, this GO :0005515: protein binding, this GO :0051082: unfolded protein binding, unfolded protein binding, visible light and biological process this GO :0018343 and protein farnesylation and biological process this GO :0030823 and regulation of cGMP metabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0051082 and unfolded protein binding and molecular function, aryl hydrocarbon receptor interacting protein-like 1 |
| Identity | 359 |
| Gene | AIPL1 |
| Long gene name | aryl hydrocarbon receptor interacting protein like 1 |
| Synonyms gene | LCA4 |
| Synonyms gene name | aryl hydrocarbon receptor-interacting protein-like 1 aryl hydrocarbon receptor interacting protein-like 1 |
| Locus | 17p13, 2 |
| Discovery year | 1999-03-18 |
| GenBank acession | AF148864 |
| Entrez gene record | 23746 |
| Pubmed identfication | 10615133 14555765 15365173 |
| RefSeq identity | NM_014336 |
| Classification | FKBP prolyl isomerases |
| Havana BLAST/BLAT | OTTHUMG00000102043 |
| Locus Specific Databases | Mutations of the Aryl Hydrocarbon Receptor-interacting Protein-like 1 |