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Anti-AKAP5 (Polyclonal), ALEXA Fluor 594

Anti-AKAP5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAKAP5
SpecificityThis antibody reacts specifically with AKAP5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human AKAP5
Gene ID9495
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), Members of this family, Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell, This family of proteins has been designated A-kinase anchoring proteins (AKAP) (1-3), To maintain this specific localization, and the DNA binding AKAP 95, display differential tissue specificity and localization (4-6), including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins, which are a network of proteins located on the internal surfaces of excitatory synapses, The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates (1)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms AKAP75 AKAP79
Also known asAKAP5 Polyclonal Antibody
Other nameAnti-AKAP5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAKAP5
Short nameAnti-AKAP5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-AKAP5 (polyclonal)
Alternative techniquepolyclonals
Identity 375
Gene AKAP5
Long gene name A-kinase anchoring protein 5
Synonyms gene name A kinase (PRKA) anchor protein 5
Locus 14q23, 3
Discovery year 1999-09-16
GenBank acession M90359
Entrez gene record 9495
Pubmed identfication 1512224 1618839
Classification A-kinase anchoring proteins
Havana BLAST/BLAT OTTHUMG00000029634

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