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Anti-ALAS-E (Polyclonal), ALEXA Fluor 594

Anti-ALAS-E (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideALAS-E
SpecificityThis antibody reacts specifically with ALAS-E
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ALAS2/ALAS-E
Gene ID212
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ALAS-E, ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells, NF-E2 and EKLF, Since the ALAS gene maps to the X chromosome, Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H, The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, The erythroid-specific isoenzyme, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver, 5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms 5 aminolevulinic acid synthase 2, 5-aminolevulinate synthase, 5-aminolevulinate synthase 2, 5-aminolevulinate synthase 2, 5-aminolevulinic acid synthase, ALAS, ALAS, ALAS E, ALAS E, ALASE, ALASE, ANH1, ANH1, ASB, Alas 2, Aminolevulinate, Aminolevulinic acid synthase 2, Delta ALA synthase 2, Delta ALA synthetase, Delta aminolevulinate synthase, Delta aminolevulinate synthase, Delta aminolevulinate synthase 2, Erythroid specic ALAS, FLJ93603, XLDPP, XLSA, XLSA, delta-, erythroid, erythroid, erythroid-specic, mitochondrial, synthase 2, 5-aminolevulinate synthase
Also known asALAS-E Polyclonal Antibody
Other nameAnti-ALAS-E Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetALAS-E
Short nameAnti-ALAS-E (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ALAS-E (polyclonal)
Alternative techniquepolyclonals

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