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Anti-ALK (Polyclonal), ALEXA Fluor 594

Anti-ALK (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideALK
SpecificityThis antibody reacts specifically with ALK
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human CD246
Gene ID238
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ALK/ATIC (chromosome 2), ALK/CLTC (chromosome 17), ALK/NPM1 (chromosome 5), ALK/RANBP2 (chromosome 2), ALK/SQSTM1 (chromosome 5), ALK/TFG (chromosome 3), ALK/TPM4 (chromosome 19), It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system, Jan 2011], LK/KIF5B (chromosome 10), The chromosomal rearrangements are the most common genetic alterations in this gene, This gene has been found to be rearranged, This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and ALK/MSN (chromosome X), and an intracellular kinase domain, and non-small cell lung cancer, including ALK (chromosome 2)/EML4 (chromosome 2), mutated, neuroblastoma, or amplified in a series of tumours including anaplastic large cell lymphomas, which belongs to the insulin receptor superfamily, which result in creation of multiple fusion genes in tumourigenesis, This gene encodes a receptor tyrosine kinase, [provided by RefSeq
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CD246
Also known asALK Polyclonal Antibody
Other nameAnti-ALK Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetALK
Short nameAnti-ALK (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-anaplastic lymphoma receptor tyrosine kinase (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target ALK and IDBG-42084 and ENSG00000171094 and 238, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, CD246 and NBLST3, Plasma membranes, this GO :0000187 and activation of MAPK activity and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004704 and NF-kappaB-inducing kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004704: NF-kappaB-inducing kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004704: NF-kappaB-inducing kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0038061 and NIK/NF-kappaB signaling and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0046777 and protein autophosphorylation and biological process this GO :0048666 and neuron development and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, anaplastic lymphoma receptor tyrosine kinase
Identity 427
Gene ALK
Long gene name anaplastic lymphoma receptor tyrosine kinase
Synonyms gene name anaplastic lymphoma kinase (Ki-1)
Locus 2p23, 1 , 2-p23
Discovery year 1993-08-24
GenBank acession D45915
Entrez gene record 238
Pubmed identfication 8122112
RefSeq identity NM_004304
Classification CD molecules Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000152034
Locus Specific Databases LRG_488

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