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Anti-Alpha B Crystallin (Polyclonal), ALEXA Fluor 594

Anti-Alpha B Crystallin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAlpha B Crystallin
SpecificityThis antibody reacts specifically with Alpha B Crystallin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Alpha B Crystallin
Gene ID1410
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Alpha and beta families are further divided into acidic and basic groups, Alpha crystallins are composed of two gene products: alpha-A and alpha-B, Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family, Alpha-A and alpha-B gene products are differentially expressed, Elevated expression of alpha-B crystallin occurs in many neurological diseases, Jul 2008], Mammalian lens crystallins are divided into alpha, Post-translational modifications decrease the ability to chaperone, Seven protein regions exist in crystallins: four homologous motifs, Since lens central fiber cells lose their nuclei during development, The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens, These heterogeneous aggregates consist of 30-40 subunits, They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture, [provided by RefSeq, a connecting peptide, a missense mutation cosegregated in a family with a desmin-related myopathy, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs, and N- and C-terminal extensions, and gamma families, and ubiquitous, beta, beta and gamma crystallins are also considered as a superfamily, for acidic and basic, instead they hold them in large soluble aggregates, making them extremely stable proteins, or enzyme, respectively, respectively, the alpha-A and alpha-B subunits have a 3:1 ratio, these crystallins are made and then retained throughout life, Crystallins are separated into two classes: taxon-specific
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HSPB5
Also known asAlpha B Crystallin Polyclonal Antibody
Other nameAnti-Alpha B Crystallin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Description- or alpha protein sometimes glycoprotein present in blood, The Anti-Alpha B Crystallin (Polyclonal) Fluor 594 is a &alpha
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAlpha B Crystallin
Short nameAnti-Alpha B Crystallin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-a B Crystallin (polyclonal)
Alternative techniquepolyclonals
Identity 2389
Gene CRYAB
Long gene name crystallin alpha B
Synonyms gene CRYA2
Synonyms gene name alpha B , crystallin
Locus 11q23, 1
Discovery year 1987-09-11
Entrez gene record 1410
Pubmed identfication 8431633
Classification Small heat shock proteins
Havana BLAST/BLAT OTTHUMG00000166885
Locus Specific Databases LOVD - Leiden Open Variation Database LRG_407

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