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Anti-Angiopoietin 2 (Polyclonal), ALEXA Fluor 594

Anti-Angiopoietin 2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAngiopoietin 2
SpecificityThis antibody reacts specifically with Angiopoietin 2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from human Angiopoietin 2
Gene ID285
Swiss ProtO15123
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Pig/Swine (Sus scrofa), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression, Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1, In concert with VEGF, In the absence of angiogenic inducers, and modulating ANGPT1 signaling, competing for the ANGPT1 binding site, it may facilitate endothelial cell migration and proliferation, such as VEGF, thus serving as a permissive angiogenic signal, Binds to TEK/TIE2
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Ang2
Also known asAngiopoietin 2 Polyclonal Antibody
Other nameAnti-Angiopoietin 2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAngiopoietin 2
Short nameAnti-Angiopoietin 2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Angiopoietin 2 (polyclonal)
Alternative techniquepolyclonals
Identity 485
Gene ANGPT2
Long gene name angiopoietin 2
Locus 8p23, 1
Discovery year 1997-07-22
GenBank acession AF004327
Entrez gene record 285
Pubmed identfication 9545648
RefSeq identity NM_001147
Classification Fibrinogen C domain containing
Havana BLAST/BLAT OTTHUMG00000090365

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