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Anti-ANKLE2 (Polyclonal), ALEXA Fluor 594

Anti-ANKLE2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideANKLE2
SpecificityThis antibody reacts specifically with ANKLE2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ANKLE2
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ANKLE2 (ankyrin repeat and LEM domain containing 2), Chromosome 12 is associated with a variety of diseases and afflictions, Exsiting as two isoforms produced by alternative splicing events, Kniest dysplasia, Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis, Noonan syndrome and trisomy 12p, achondrogenesis, also known as LEMD7, including hypochondrogenesis, is a 938 amino acid single-pass membrane protein containing an ANK repeat and a LEM domain, the gene encoding ANKLE2 maps to human chromosome 12, which causes facial developmental defects and seizure disorders, which encodes over 1, 100 genes and comprises approximately 4, 5% of the human genome, Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LEMD7 Lem4
Also known asANKLE2 Polyclonal Antibody
Other nameAnti-ANKLE2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetANKLE2
Short nameAnti-ANKLE2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ANKLE2 (polyclonal)
Alternative techniquepolyclonals
Identity 29101
Gene ANKLE2
Long gene name ankyrin repeat and LEM domain containing 2
Synonyms gene KIAA0692
Synonyms gene name KIAA0692
Synonyms name LEM domain containing 7
Locus 12q24, 33
Discovery year 2006-01-17
GenBank acession AB014592
Entrez gene record 23141
Pubmed identfication 9734811
Classification Ankyrin repeat domain containing LEM domain containing
Havana BLAST/BLAT OTTHUMG00000168046

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