Name : Anti-ANKRD11 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2209610388
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ANKRD11 |
| Specificity | This antibody reacts specifically with ANKRD11 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human ANKRD11 |
| Gene ID | 29123 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Ankyrin-repeat proteins have been associated with a number of human diseases, It contains three functional domains: a conserved N-terminal ankyrin repeat domain (ARD(consisting of 22â, It has been studied using multiple sequence alignment to determine which conserved amino acid residues are critical for folding and stability, The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops, a spectrin binding domain and a variably sized C-terminal regulatory domain, most notably, the cell cycle inhibitor p16 is associated with cancer and the Notch protein is a key component of cell signaling pathways whose intracellular repeat domain is disrupted in mutations that give rise to the neurological disorder known as CADASIL, &euro, &ldquo, 24 tandem repeats of 33 amino acids), Ankyrin is a membrane protein that mediates the attachment of the erythrocyte membrane skeleton to the plasma membrane and interacts with CD44 and inositol triphosphate |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | LZ16 T13 |
| Also known as | ANKRD11 Polyclonal Antibody |
| Other name | Anti-ANKRD11 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ANKRD11 |
| Short name | Anti-ANKRD11 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-ANKRD11 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 21316 |
| Gene | ANKRD11 |
| Long gene name | ankyrin repeat domain 11 |
| Locus | 16q24, 3 |
| Discovery year | 2004-01-15 |
| GenBank acession | AY373756 |
| Entrez gene record | 29123 |
| Pubmed identfication | 11483580 |
| RefSeq identity | NM_013275 |
| Classification | Ankyrin repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000175548 |