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Anti-APOBEC3B (Polyclonal), ALEXA Fluor 594

Anti-APOBEC3B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAPOBEC3B
SpecificityThis antibody reacts specifically with APOBEC3B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human APOBEC3B
Gene ID9582
Swiss ProtQ9UH17
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, Exhibits antiviral activity against simian immunodeficiency virus (SIV), Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA, The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, hepatitis B virus (HBV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA, together exert efficient antiretroviral effects in infected target cells, DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PHRBNL FLJ21201
Also known asAPOBEC3B Polyclonal Antibody
Other nameAnti-APOBEC3B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAPOBEC3B
Short nameAnti-APOBEC3B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-APOBEC3B (polyclonal)
Alternative techniquepolyclonals
Identity 17352
Gene APOBEC3B
Long gene name apolipoprotein B mRNA editing enzyme catalytic subunit 3B
Synonyms gene name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
Synonyms name phorbolin 3
Locus 22q13, 1
Discovery year 2001-12-12
GenBank acession AK024854
Entrez gene record 9582
Pubmed identfication 11863358 10469298
RefSeq identity NM_004900
Classification Apolipoprotein B mRNA editing enzyme catalytic subunits Minor histocompatibility antigens
Havana BLAST/BLAT OTTHUMG00000151085

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