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Anti-APOBEC3C (Polyclonal), ALEXA Fluor 594

Anti-APOBEC3C (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAPOBEC3C
SpecificityThis antibody reacts specifically with APOBEC3C
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human APOBEC3C
Gene ID27350
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, Interestingly, Like APOBEC3G, The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22, This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention, Thus, Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome, and are also likely contribute to sequence variation observed in many viruses, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, resulting in G to A hypermutation in the plus strand of DNA, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication, APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms APOBEC1L PBI bK150C2, 3 ARDC2 ARDC4 ARP5
Also known asAPOBEC3C Polyclonal Antibody
Other nameAnti-APOBEC3C Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAPOBEC3C
Short nameAnti-APOBEC3C (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-APOBEC3C (polyclonal)
Alternative techniquepolyclonals
Identity 17353
Gene APOBEC3C
Long gene name apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Synonyms gene name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Locus 22q13, 1
Discovery year 2001-12-12
GenBank acession AF165520
Entrez gene record 27350
Pubmed identfication 11863358
RefSeq identity NM_014508
Classification Apolipoprotein B mRNA editing enzyme catalytic subunits
Havana BLAST/BLAT OTTHUMG00000151087

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