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Anti-Apolipoprotein B (Polyclonal), ALEXA Fluor 594

Anti-Apolipoprotein B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideApoB
SpecificityThis antibody reacts specifically with Apolipoprotein B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Apolipoprotein B
Gene ID338
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A disorder characterized by highly reduced plasma concentrations of low density lipoproteins, Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor, Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia, FDB is a dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease (CAD), LDL (apo B-100) and VLDL (apo B-100), The plasma cholesterol levels are dramatically elevated due to impaired clearance of LDL particles by defective APOB/E receptors, and dietary fat malabsorption, Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), Defects in APOB are a cause of familial ligand-defective apolipoprotein B-100 (FDB), Involvement in disease: Defects in APOB are a cause of hypobetalipoproteinemia familial type 1 (FHBL1)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asApolipoprotein B Polyclonal Antibody
Other nameAnti-Apolipoprotein B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetApolipoprotein B
Short nameAnti-Apolipoprotein B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Apolipoprotein B (polyclonal)
Alternative techniquepolyclonals
Identity 603
Gene APOB
Long gene name apolipoprotein B
Synonyms gene name apolipoprotein B (including Ag(x) antigen)
Locus 2p24, 1
Discovery year 2001-06-22
GenBank acession M14162
Entrez gene record 338
Classification Apolipoproteins
Havana BLAST/BLAT OTTHUMG00000090785

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