Name : Anti-APXL (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3992560793
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | APXL |
| Specificity | This antibody reacts specifically with APXL |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human APXL |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | APXL interacts with F-Actin and is thought to mediate endothelial cell morphology during cell spreading, APXL is expressed in kidney, Containing one ASD1 domain, In conjunction with chromosome Y, The gene encoding APXL maps to human chromosome X, There are a number of conditions related to an abnormal number and combination of sex chromosomes, Tubulin redistribution, brain, chromosome X is responsible for sex determination, color blindness, hemophilia and Duchenne muscular dystrophy, including the cytoplasm, lung, one ASD2 domain and one PDZ domain, pancreas and placenta and is overexpressed in melanomas, possibly regulating melanosome biogenesis and inducing Î, some of which include Turner's syndrome, suggesting a role in tumor transformation and metastasis, the cell junction and the apical cell membrane, the cytoskeleton, which contains nearly 153 million base pairs and houses over 1, ³, 000 genes, 616 amino acid protein that localizes to a variety of locations within the cell, APXL is a 1 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | APXL Polyclonal Antibody |
| Other name | Anti-APXL Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | APXL |
| Short name | Anti-APXL (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-APXL (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 630 |
| Gene | SHROOM2 |
| Long gene name | shroom family member 2 |
| Synonyms gene | APXL |
| Synonyms gene name | Xenopus laevis-like apical protein-like (Xenopus laevis) , apical protein |
| Locus | Xp22, 2 |
| Discovery year | 1995-06-13 |
| GenBank acession | X83543 |
| Entrez gene record | 357 |
| Pubmed identfication | 7795590 16615870 |
| RefSeq identity | NM_001649 |
| Classification | PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000021121 |
| Locus Specific Databases | Mental Retardation database |