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Anti-AQP0 (Polyclonal), ALEXA Fluor 594

Anti-AQP0 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAQP0
SpecificityThis antibody reacts specifically with AQP0
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human AQP0
Gene ID4284
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Aquaporin 0 or MIP26 (major intrinsic protein 26kD), Aquaporin families of proteins are predicted to contain six transmembrane domains, Defects in Aquaporin 0 are a cause of autosomal recessive congenital cataract, Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family, Interestingly, Mammalian red cells, The N and C terminus are predicted to be cytoplasmic, The lens opacity mutation (LOP) is an AA substitution that inhibits targeting of MIP to the cell membrane, The lens specific Aquaporin 0 represents up to 80% of total lens membrane protein, Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein aquaporins, and Aquaporin 1 has been the foundation of the growing family of aquaporins, and descending thin limb of Henle are extraordinarily permeable to water, renal proximal tubules, tissue membranes show a great degree of water permeability, Water is a critical component of all living cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MP26 LIM1 AQP0
Also known asAQP0 Polyclonal Antibody
Other nameAnti-AQP0 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAQP0
Short nameAnti-AQP0 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-AQP0 (polyclonal)
Alternative techniquepolyclonals
Identity 7103
Gene MIP
Long gene name major intrinsic protein of lens fiber
Synonyms name aquaporin 0
Locus 12q13
Discovery year 2001-06-22
Entrez gene record 4284
Pubmed identfication 1840563 7536742
RefSeq identity NM_012064
Classification Aquaporins
Havana BLAST/BLAT OTTHUMG00000170571

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