Name : Anti-ARHGEF18 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4969514611
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ARHGEF18 |
| Specificity | This antibody reacts specifically with ARHGEF18 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human ARHGEF18/p114RhoGEF |
| Gene ID | 23370 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs), Alternatively spliced transcript variants encoding different isoforms have been identified, Family members share a common feature, Oct 2008], The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family, These cellular processes include cytoskeletal rearrangements, [provided by RefSeq, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain, cell growth and motility, gene transcription, Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | P114-RhoGEF KIAA0521 MGC15913 |
| Also known as | ARHGEF18 Polyclonal Antibody |
| Other name | Anti-ARHGEF18 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ARHGEF18 |
| Short name | Anti-ARHGEF18 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Rho/Rac guanine nucleotide exchange factor (GEF) 18 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | ARHGEF18 and IDBG-22691 and ENSG00000104880 and 23370, Cell surfaces, Rho guanyl-nucleotide exchange factor activity, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030054 and cell junction and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0045177 and apical part of cell and cellular component this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005089: Rho guanyl-nucleotide exchange factor activity, this GO :0005089: Rho guanyl-nucleotide exchange factor activity, Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| Identity | 17090 |
| Gene | ARHGEF18 |
| Long gene name | Rho/Rac guanine nucleotide exchange factor 18 |
| Synonyms gene name | rho/rac guanine nucleotide exchange factor (GEF) 18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| Synonyms name | Rho-specific guanine nucleotide exchange factor p114 |
| Locus | 19p13, 2 |
| Discovery year | 2004-01-09 |
| GenBank acession | AK074372 |
| Entrez gene record | 23370 |
| Pubmed identfication | 9628581 11318610 |
| RefSeq identity | NM_015318 |
| Classification | Rho guanine nucleotide exchange factors Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000177342 |