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Anti-ARP2/ARP3 (Polyclonal), ALEXA Fluor 594

Anti-ARP2/ARP3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideARP2/ARP3
SpecificityThis antibody reacts specifically with ARP2/ARP3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ARP2/ARP3
Gene ID10097
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Cells trigger actin polymerization through either the de novo nucleation of filaments from monomeric actin, In addition, In response to GTP-binding Cdc42, The Arp2/3 complex consists of the actin-related proteins Arp2 and Arp3, The Arp2/3 complex promotes actin nucleation by binding the pointed end of actin filaments, The nucleation of actin is a rate-limiting and unfavorable reaction in actin polymerization and therefore requires the involvement of the Arp2/3 complex, and initiates the formation of lamellipodia and filopodia, and nucleates growth in the barbed direction, and platelet activation, and various other accessory proteins, cell adhesion, cell migration, including chemotaxis, namely the WASP proteins, or by associating with the side of an existing filament, or the uncapping of existing barbed ends, the Arp2/3 complex also mediates actin cytoskeletal outgrowths that are regulated by the Rho family of small GTPases, the Arp2/3 complex binds the Cdc42 substrates, the severing of existing filaments to create uncapped barbed ends, which helps create new filaments and promotes the end-to-side cross-linking of actin filaments into the branching meshwork, Actin polymerization is required for a variety of cell functions
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ARP2
Also known asARP2/ARP3 Polyclonal Antibody
Other nameAnti-ARP2/ARP3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetARP2/ARP3
Short nameAnti-ARP2/ARP3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ARP2/ARP3 (polyclonal)
Alternative techniquepolyclonals
Identity 169
Gene ACTR2
Long gene name ARP2 actin related protein 2 homolog
Synonyms gene name ARP2 (actin-related protein 2, yeast) homolog ARP2 actin-related protein 2 homolog (yeast)
Locus 2p14
Discovery year 1999-05-17
GenBank acession AF006082
Entrez gene record 10097
Pubmed identfication 9230079
RefSeq identity NM_001005386
Classification Actin related protein 2/3 complex
Havana BLAST/BLAT OTTHUMG00000129540

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