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Anti-ARRDC4 (Polyclonal), ALEXA Fluor 594

Anti-ARRDC4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideARRDC4
SpecificityThis antibody reacts specifically with ARRDC4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ARRDC4
Gene ID91947
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs), Different arrestins (visual arrestin (or Arrestin 1), GPCRs activate a heterotrimeric G protein, In order to turn off this response, In response to a stimulus, Once arrestin is bound to the receptor it is unable to signal further, Recent research continues to expand the known actions of arrestins, The arrestins are a family of proteins that are important for regulating signal transduction within cells, The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs), This phosphorylation specifically marks the activated receptor for arrestin binding, activated receptors need to be silenced, beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways, or adapt to a constant stimulus, which can bind to other classes of receptors and can directly activate signaling pathways on their own, ARRDC4 belongs to the arrestin family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ36045
Also known asARRDC4 Polyclonal Antibody
Other nameAnti-ARRDC4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetARRDC4
Short nameAnti-ARRDC4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ARRDC4 (polyclonal)
Alternative techniquepolyclonals
Identity 28087
Gene ARRDC4
Long gene name arrestin domain containing 4
Locus 15q26, 2
Discovery year 2004-02-11
GenBank acession BC028704
Entrez gene record 91947
Pubmed identfication 12477932
RefSeq identity NM_183376
Classification Alpha arrestins
Havana BLAST/BLAT OTTHUMG00000149849

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