Name : Anti-ASB17 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN9905726034
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ASB17 |
| Specificity | This antibody reacts specifically with ASB17 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human ASB17 |
| Gene ID | 127247 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | ASB-17 contains one ankyrin repeat and one SOCS box domain, ASB-17 is a 295 amino acid member of this family, ASB-17 is thought to be a substrate-recognition subunit of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin protein ligase complex, Members of the ASB family include ASB-1 through ASB-18 and are involved in a variety of biological processes, Several other families of proteins also contain SOCS boxes, The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family, This complex mediates the ubiquitination of target proteins and their subsequent proteasomal degradation, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B and C complex, Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | ASB17 Polyclonal Antibody |
| Other name | Anti-ASB17 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ASB17 |
| Short name | Anti-ASB17 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-ASB17 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 19769 |
| Gene | ASB17 |
| Long gene name | ankyrin repeat and SOCS box containing 17 |
| Synonyms gene name | ankyrin repeat and SOCS box-containing 17 |
| Locus | 1p31, 1 |
| Discovery year | 2002-12-03 |
| GenBank acession | AF403035 |
| Entrez gene record | 127247 |
| Pubmed identfication | 12076535 |
| RefSeq identity | NM_080868 |
| Classification | Ankyrin repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000009787 |