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Anti-ASB3 (Polyclonal), ALEXA Fluor 594

Anti-ASB3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideASB3
SpecificityThis antibody reacts specifically with ASB3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ASB3
Gene ID51130
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ASB-1 is expressed in multiple organs, ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules, ASB-2, ASB-2 is directly induced by all-trans retinotic acid, ASB-3 and ASB-4, Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells, Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter, including the hematopoietic compartment, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex, Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ASB-3
Also known asASB3 Polyclonal Antibody
Other nameAnti-ASB3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetASB3
Short nameAnti-ASB3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ASB3 (polyclonal)
Alternative techniquepolyclonals
Identity 16013
Gene ASB3
Long gene name ankyrin repeat and SOCS box containing 3
Synonyms gene name ankyrin repeat and SOCS box-containing 3
Locus 2p16, 2
Discovery year 2001-06-29
GenBank acession AK000985
Entrez gene record 51130
Pubmed identfication 15899873
RefSeq identity NM_016115
Classification Ankyrin repeat domain containing
Havana BLAST/BLAT OTTHUMG00000184778

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