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Anti-ASK1 (Ser1033) (Polyclonal), ALEXA Fluor 594

Anti-ASK1 (Ser1033) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideASK1 Ser1033
SpecificityThis antibody reacts specifically with ASK1 (Ser1033)
ModificationPhosphorylation
Modification siteSer1033
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human ASK1 around the phosphorylation site of Ser1033
Gene ID4217
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Drosophila, MAPK kinase (MKK or MEK), MAPK kinase/MEK, MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPKK4) in vitro, MAPKKK5 contains 1, MAPKKK5 does not activate MAPK/ERK, Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas, The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, The kinases of these signaling cascades are highly conserved, and MAPK kinase kinase (MAPKKK or MEKK), and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells, and homologs exist in yeast, and mammalian cells, which in turn activates MAPK, 374 amino acids with all 11 kinase subdomains, Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MAPKKK5 ASK1
Also known asASK1 (Ser1033) Polyclonal Antibody
Other nameAnti-ASK1 (Ser1033) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetASK1 (Ser1033)
Short nameAnti-ASK1 (Ser1033) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ASK1 (Ser1033) (polyclonal)
Alternative techniquepolyclonals
Identity 6857
Gene MAP3K5
Long gene name mitogen-activated protein kinase kinase kinase 5
Synonyms gene MEKK5
Synonyms name apoptosis signal regulating kinase 1
Locus 6q23, 3
Discovery year 1997-11-14
GenBank acession U67156
Entrez gene record 4217
Pubmed identfication 9465908
Classification Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT OTTHUMG00000015647
Locus Specific Databases The Globin Gene Server

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