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Anti-ATF4 (Ser245) (Polyclonal), ALEXA Fluor 594

Anti-ATF4 (Ser245) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideATF4 Ser245
SpecificityThis antibody reacts specifically with ATF4 (Ser245)
ModificationPhosphorylation
Modification siteSer245
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human ATF4 around the phosphorylation site of Ser245
Gene ID468
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2), The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, These transcription factors share a leucine zipper region that is involved in protein-protein interactions, cAMP-response element binding proteins (CREBs) and CREB-like proteins, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene), ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms TAXREB67 CREB-2
Also known asATF4 (Ser245) Polyclonal Antibody
Other nameAnti-ATF4 (Ser245) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetATF4 (Ser245)
Short nameAnti-ATF4 (Ser245) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ATF4 (Ser245) (polyclonal)
Alternative techniquepolyclonals
Identity 786
Gene ATF4
Long gene name activating transcription factor 4
Synonyms gene TXREB
Synonyms gene name activating transcription factor 4 (tax-responsive enhancer element B67)
Synonyms name tax-responsive enhancer element B67
Locus 22q13, 1
Discovery year 1992-06-09
GenBank acession D90209
Entrez gene record 468
Pubmed identfication 1847461 1534408
RefSeq identity NM_001675
Classification Basic leucine zipper proteins
Havana BLAST/BLAT OTTHUMG00000151099

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