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Anti-ATG18/WIPI1 (Polyclonal), ALEXA Fluor 594

Anti-ATG18/WIPI1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideATG18/WIPI1
SpecificityThis antibody reacts specifically with ATG18/WIPI1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from mouse WIPI1
Gene ID55062
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Consistent with this, Overexpression of WIPI1 disrupted the function of the MPR pathway, Suppression of WIPI1 by interfering RNA indicated that WIPI1 is required for normal endosomal organization and distribution of IGF2R, WIPI1 moved through the same set of endosomal membranes as that followed by mannose-6-phosphate receptor (MPR), WIPI1 was enriched in clathrin-coated vesicles, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids, phosphoinositide interacting 1), such as WIPI1 (WD repeat domain, whereas expression of a double point mutant unable to bind phosphoinositides had no effect, Members of the WIPI subfamily of WD40 repeat proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ10055 WIPI49 ATG18 ATG18A
Also known asATG18/WIPI1 Polyclonal Antibody
Other nameAnti-ATG18/WIPI1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetATG18/WIPI1
Short nameAnti-ATG18/WIPI1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ATG18/WIPI1 (polyclonal)
Alternative techniquepolyclonals
Identity 25471
Gene WIPI1
Long gene name WD repeat domain, phosphoinositide interacting 1
Locus 17q24, 2
Discovery year 2005-11-15
Entrez gene record 55062
Pubmed identfication 15020712 15602573
RefSeq identity NM_017983
Classification Autophagy related WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000179873

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