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Anti-ATG3 (Tyr18) (Polyclonal), ALEXA Fluor 594

Anti-ATG3 (Tyr18) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideATG3 Tyr18
SpecificityThis antibody reacts specifically with ATG3 (Tyr18)
ModificationPhosphorylation
Modification siteTyr18
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human ATG3 around the phosphorylation site of Tyr18
Gene ID64422
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy, ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3, Also acts as an autocatalytic E2-like enzyme, Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE), PE-conjugation to ATG8-like proteins is essential for autophagy, Preferred substrate is MAP1LC3A, catalyzing the conjugation of ATG12 to itself, E2-like enzyme involved in autophagy and mitochondrial homeostasis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PC3-96 FLJ22125 MGC15201 DKFZp564M1178
Also known asATG3 (Tyr18) Polyclonal Antibody
Other nameAnti-ATG3 (Tyr18) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetATG3 (Tyr18)
Short nameAnti-ATG3 (Tyr18) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-autophagy related 3 (Tyr18) (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target ATG3 and IDBG-49891 and ENSG00000144848 and 64422, ATG3 and IDBG-632300 and ENSBTAG00000009084 and 508571, Atg3 and IDBG-162821 and ENSMUSG00000022663 and 67841, Cytoplasm, enzyme binding, this GO :0000045 and autophagic vacuole assembly and biological process this GO :0000153 and cytoplasmic ubiquitin ligase complex and cellular component this GO :0000422 and mitochondrion degradation and biological process this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006464 and cellular protein modification process and biological process this GO :0006612 and protein targeting to membrane and biological process this GO :0006914 and autophagy and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0019776 and Atg8 ligase activity and molecular function this GO :0019777 and Atg12 ligase activity and molecular function this GO :0019787 and small conjugating protein ligase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0043653 and mitochondrial fragmentation involved in apoptotic process and biological process this GO :0044804 and nucleophagy and biological process this GO :1902017 and regulation of cilium assembly and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0019776: Atg8 ligase activity and also this GO :0019777: Atg12 ligase activity and also this GO :0019787: small conjugating protein ligase activity and also this GO :0019899: enzyme binding, this GO :0019776: Atg8 ligase activity, this GO :0019777: Atg12 ligase activity, this GO :0019787: small conjugating protein ligase activity, this GO :0019899: enzyme binding, autophagy related 3
Identity 20962
Gene ATG3
Long gene name autophagy related 3
Synonyms gene APG3L
Synonyms gene name APG3 autophagy 3-like (S, cerevisiae) , cerevisiae) ATG3 autophagy related 3 homolog (S
Locus 3q13, 2
Discovery year 2004-07-05
Entrez gene record 64422
Pubmed identfication 11825910
RefSeq identity NM_022488
Classification Autophagy related
Havana BLAST/BLAT OTTHUMG00000159260

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