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Anti-ATX2 (Polyclonal), ALEXA Fluor 594

Anti-ATX2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideATX2
SpecificityThis antibody reacts specifically with ATX2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ATX2
Gene ID6311
Swiss ProtQ99700
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ADCA has been divided into three groups: ADCA types I-III, ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2, Clinically, Longer expansions result in earlier onset of the disease, There are four named isoforms, brain stem and spinal cord, bulbar and extrapyramidal signs, ophthalmoplegia, peripheral neuropathy and dementia, The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ATX2
Also known asATX2 Polyclonal Antibody
Other nameAnti-ATX2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetATX2
Short nameAnti-ATX2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ATX2 (polyclonal)
Alternative techniquepolyclonals
Identity 10555
Gene ATXN2
Long gene name ataxin 2
Synonyms gene SCA2 TNRC13
Synonyms gene name ataxin 2) , autosomal dominant, spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2
Synonyms name trinucleotide repeat containing 13
Locus 12q24, 12
Discovery year 1991-08-06
GenBank acession U80749
Entrez gene record 6311
Pubmed identfication 8358438 9225980
RefSeq identity NM_002973
Classification Ataxins Trinucleotide repeat containing
Havana BLAST/BLAT OTTHUMG00000133475
Locus Specific Databases LRG_864

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