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Anti-ATXN10/SCA10 (Polyclonal), ALEXA Fluor 594

Anti-ATXN10/SCA10 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideATXN10/SCA10
SpecificityThis antibody reacts specifically with ATXN10/SCA10
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ATXN10/SCA10
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A loss of ataxin-10 in primary neuronal cells causes increased apoptosis of cerebellar neurons, Ataxin-10 interacts with p110, Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins, SCA is caused by the expansion of a translated CAG repeat, SCA10 is caused by an expansion of an ATTCT pentanucleotide repeat in intron 9 of the ataxin-10 gene, Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant disorder that causes cerebellar ataxia and seizures, The ataxin proteins are ubiquitously expressed in nervous tissue, an O-Linked beta-N-acetylglucosamine transferase, and may be important in the regulation of intracellular glycosylation levels and homeostasis in the brain, brain stem and spinal cord in the central nervous system, but are primarily detected in cerebellum, encoding a polyglutamine tract in SCA gene products, known as ataxins, Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms E46L FLJ37990
Also known asATXN10/SCA10 Polyclonal Antibody
Other nameAnti-ATXN10/SCA10 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetATXN10/SCA10
Short nameAnti-ATXN10/SCA10 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ATXN10/SCA10 (polyclonal)
Alternative techniquepolyclonals
Identity 10549
Gene ATXN10
Long gene name ataxin 10
Synonyms gene SCA10
Synonyms gene name spinocerebellar ataxia 10
Locus 22q13, 31
Discovery year 1999-04-16
GenBank acession AK095309
Entrez gene record 25814
Pubmed identfication 9973298
RefSeq identity NM_013236
Classification Ataxins
Havana BLAST/BLAT OTTHUMG00000150451

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