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Anti-ATXN3L (Polyclonal), ALEXA Fluor 594

Anti-ATXN3L (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideATXN3L
SpecificityThis antibody reacts specifically with ATXN3L
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ATXN3L
Gene ID92552
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Longer expansions result in earlier onset and more severe clinical manifestations of the disease, Patients show progressive incoordination of gait and often poor coordination of hands, SCA3 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, The molecular defect in SCA3 is the a CAG repeat expansion in ATXN3 coding region, also known as Machado-Joseph disease (MJD), bulbar and extrapyramidal signs, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, ophthalmoplegia, peripheral neuropathy and dementia, speech and eye movements, Defects in ATXN3 are the cause of spinocerebellar ataxia type 3 (SCA3)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MJDL
Also known asATXN3L Polyclonal Antibody
Other nameAnti-ATXN3L Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetATXN3L
Short nameAnti-ATXN3L (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ATXN3L (polyclonal)
Alternative techniquepolyclonals
Identity 24173
Gene ATXN3L
Long gene name ataxin 3 like
Synonyms gene name ataxin 3-like
Locus Xp22, 2
Discovery year 2004-08-20
Entrez gene record 92552
RefSeq identity NM_001135995
Classification MJD deubiquinating enzymes
Havana BLAST/BLAT OTTHUMG00000021146
Locus Specific Databases Mental Retardation database

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