Name : Anti-BBS7 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3084397511
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | BBS7 |
| Specificity | This antibody reacts specifically with BBS7 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human BBS7 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | BBS is a heterogeneous disorder mapping to eight genetic loci and encoding eight proteins, BBS patients also have an increased risk of developing diabetes, BBS1-BBS8, BBS2 contains two overlapping genes: BBS2L1 and BBS2L2, BBS7 contains 672 amino acids and is expressed at low to moderate levels in most human tissues, BBSL1 was re-named BBS7, Five BBS proteins encode basal body or cilia proteins, and congenital heart defects, and developmental delay, hypertension, hypogenitalism, photoreceptor degeneration, polydactyly, renal abnormalities, suggesting that BBS is a ciliary dysfunction disorder, whereas BBS2L2 independently funcitons as BBS1, Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ10715 BBS2L1 |
| Also known as | BBS7 Polyclonal Antibody |
| Other name | Anti-BBS7 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | BBS7 |
| Short name | Anti-BBS7 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Bardet-Biedl syndrome 7 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | BBS7 and IDBG-36452 and ENSG00000138686 and 55212, BBS7 and IDBG-639728 and ENSBTAG00000004945 and 100138953, Bbs7 and IDBG-138825 and ENSMUSG00000037325 and 71492, nuclei, protein binding, this GO :0001103 and RNA polymerase II repressing transcription factor binding and molecular function this GO :0001654 and eye development and biological process this GO :0001947 and heart looping and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005930 and axoneme and cellular component this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007368 and determination of left/right symmetry and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0007601 and visual perception and biological process this GO :0008104 and protein localization and biological process this GO :0015031 and protein transport and biological process this GO :0032402 and melanosome transport and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034464 and BBSome and cellular component this GO :0035058 and nonmotile primary cilium assembly and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0045444 and fat cell differentiation and biological process this GO :0048546 and digestive tract morphogenesis and biological process this GO :0051877 and pigment granule aggregation in cell center and biological process this GO :0060021 and palate development and biological process this GO :0060170 and ciliary membrane and cellular component this GO :0060173 and limb development and biological process this GO :0060271 and cilium morphogenesis and biological process, this GO :0001103: RNA polymerase II repressing transcription factor binding, this GO :0001103: RNA polymerase II repressing transcription factor binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, Bardet-Biedl syndrome 7 |
| Identity | 18758 |
| Gene | BBS7 |
| Long gene name | Bardet-Biedl syndrome 7 |
| Locus | 4q27 |
| Discovery year | 2003-02-05 |
| GenBank acession | AF521644 |
| Entrez gene record | 55212 |
| Classification | Bardet-Biedl syndrome associated BBSome |
| Havana BLAST/BLAT | OTTHUMG00000133076 |
| Locus Specific Databases | Mutations of the Bardet-Biedl Syndrome Type 7 Gene (BBS2L1) |