Name : Anti-BBS9 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3255101083
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | BBS9 |
| Specificity | This antibody reacts specifically with BBS9 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human BBS9 |
| Gene ID | 27241 |
| Swiss Prot | Q3SYG4 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane, Required for proper BBSome complex assembly and its ciliary localization, The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function, This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane, which localizes to the basal body and contacts the BBSome, The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | B1 PTHB1 |
| Also known as | BBS9 Polyclonal Antibody |
| Other name | Anti-BBS9 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | BBS9 |
| Short name | Anti-BBS9 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Bardet-Biedl syndrome 9 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | BBS9 and IDBG-11848 and ENSG00000122507 and 27241, BBS9 and IDBG-633236 and ENSBTAG00000006528 and 535387, Bbs9 and IDBG-144106 and ENSMUSG00000035919 and 319845, Cytoplasm, protein binding, this GO :0003674 and molecular function and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005815 and microtubule organizing center and cellular component this GO :0005929 and cilium and cellular component this GO :0007601 and visual perception and biological process this GO :0015031 and protein transport and biological process this GO :0030030 and cell projection organization and biological process this GO :0034464 and BBSome and cellular component this GO :0042384 and cilium assembly and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0050896 and response to stimulus and biological process this GO :0060170 and ciliary membrane and cellular component, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0005515: protein binding, this GO :0005515: protein binding, Bardet-Biedl syndrome 9 |
| Identity | 30000 |
| Gene | BBS9 |
| Long gene name | Bardet-Biedl syndrome 9 |
| Synonyms name | parathyroid hormone responsive B1 gene |
| Locus | 7p14, 3 |
| Discovery year | 2007-01-18 |
| Entrez gene record | 27241 |
| Pubmed identfication | 16380913 10221542 |
| Classification | Bardet-Biedl syndrome associated BBSome |
| Havana BLAST/BLAT | OTTHUMG00000128659 |