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Anti-BCAR1(Tyr410) (Polyclonal), ALEXA Fluor 594

Anti-BCAR1(Tyr410) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Price 516
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBCAR1 Tyr410
SpecificityWill recognize BCAR1(Tyr414) in mouse and BCAR1(Tyr508) in ratBCAR1(Tyr410)
ModificationPhosphorylation
Modification siteTyr410
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Cell membrane, Cytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human BCAR1 around the phosphorylation site of Tyr410
Gene ID9564
Swiss ProtP56945
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Implicated in induction of cell migration, Overexpression confers antiestrogen resistance on breast cancer cells, Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms P130Cas Crkas CAS CASS1
Also known asBCAR1(Tyr410) Polyclonal Antibody
Other nameAnti-BCAR1(Tyr410) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetBCAR1(Tyr410)
Short nameAnti-BCAR1(Tyr410) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-breast cancer antibody to-estrogen resistance 1(Tyr410) (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BCAR1 and IDBG-42468 and ENSG00000050820 and 9564, BCAR1 and IDBG-629067 and ENSBTAG00000012002 and, Bcar1 and IDBG-193577 and ENSMUSG00000031955 and 12927, CAS and CAS1 and CASS1 and CRKAS and P130Cas, nuclei, protein kinase binding, this GO :0001558 and regulation of cell growth and biological process this GO :0001726 and ruffle and cellular component this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0007015 and actin filament organization and biological process this GO :0007155 and cell adhesion and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008283 and cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0016477 and cell migration and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030168 and platelet activation and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0035729 and cellular response to hepatocyte growth factor stimulus and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0048008 and platelet-derived growth factor receptor signaling pathway and biological process this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048012 and hepatocyte growth factor receptor signaling pathway and biological process this GO :0050851 and antigen receptor-mediated signaling pathway and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0051301 and cell division and biological process this GO :0060326 and cell chemotaxis and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0017124: SH3 domain binding and also this GO :0019901: protein kinase binding, this GO :0005515: protein binding, this GO :0017124: SH3 domain binding, this GO :0019901: protein kinase binding, breast cancer anti-estrogen resistance 1
Identity 971
Gene BCAR1
Long gene name BCAR1, Cas family scaffolding protein
Synonyms gene name breast cancer anti-estrogen resistance 1
Synonyms name Crk-associated substrate Cas scaffolding protein family member 1
Locus 16q23, 1
Discovery year 1999-04-29
GenBank acession AJ242987
Entrez gene record 9564
Pubmed identfication 8413311 10639512
RefSeq identity NM_014567
Classification Cas scaffolding proteins
Havana BLAST/BLAT OTTHUMG00000137604

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