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Anti-Bcl-2 Antibody

Anti-Bcl-2 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAnti-Bcl-2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the anti-Bcl-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis anti-Bcl-2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P10415
PurityAntigen affinity
Description Appears to function in a feedback loop system with caspases, Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1), Regulates cell death by controlling the mitochondrial membrane permeability, Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells
ImmunogenA portion of amino acids 49-76 from the human protein was used as the immunogen for this anti-Bcl-2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the anti-Bcl-2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetBcl-2
Short nameAnti-Bcl-2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameantibody to-Bcl-2 (Antibody to)
Alternative techniqueantibodies
Identity 990
Gene BCL2
Long gene name BCL2, apoptosis regulator
Synonyms gene name B-cell CLL/lymphoma 2
Synonyms Bcl-2 PPP1R50
Synonyms name protein phosphatase 1, regulatory subunit 50
Locus 18q21, 33
Discovery year 2001-06-22
GenBank acession M14745
Entrez gene record 596
RefSeq identity NM_000633 NM_000657
Classification Protein phosphatase 1 regulatory subunits BCL2 family
Havana BLAST/BLAT OTTHUMG00000132791
Locus Specific Databases LRG_1113

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