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Anti-Bcl-xL (Thr115) (Polyclonal), ALEXA Fluor 594

Anti-Bcl-xL (Thr115) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBcl-xL Thr115
SpecificityThis antibody reacts specifically with Bcl-xL (Thr115)
ModificationPhosphorylation
Modification siteThr115
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Mitochondrion, Cytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human BCL2L1 around the phosphorylation site of Thr115
Gene ID598
Swiss ProtQ07817
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis, Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, During synaptic stimulation, Inhibits activation of caspases, Isoform Bcl-X(L) also regulates presynaptic plasticity, Isoform Bcl-X(S) promotes apoptosis, from the mitochondrial membrane, including neurotransmitter release and recovery, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles, number of axonal mitochondria as well as size and number of synaptic vesicle clusters, Potent inhibitor of cell death
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Apoptosis regulator Bcl-X, BCL-XL/S, BCL2L, BCL2L1, BCLXL, BCLXS, Bcl-2-like protein 1, Bcl-X, Bcl2-L-1, PPP1R52, bcl-xL, bcl-xS, BCLX
Also known asBcl-xL (Thr115) Polyclonal Antibody
Other nameAnti-Bcl-xL (Thr115) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetBcl-xL (Thr115)
Short nameAnti-Bcl-xL (Thr115) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Bcl-xL (Thr115) (polyclonal)
Alternative techniquepolyclonals

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