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Anti-Bcl2 modifying factor, ALEXA Fluor 594

Anti-Bcl2 modifying factor, ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBcl2 modying factor
SpecificityThis antibody reacts specifically with Bcl2 modifying factor
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Bcl2 modifying factor
Gene ID90427
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information BID, Bad, Bcl-2 modifying factor (Bmf) is a BH3-only protein that binds prosurvival Bcl-2 family members to initiate apoptosis, Bik, Bim, Binding results in a caspase cascade leading to apoptosis, Bmf is sequestered to Myosin V motors on Actin in the cytoskeleton by associating with Dynein light chain 2 (DLC2) homodimers, Bmf is widely expressed in tissues such as pancreas, Bmf then translocates to the mitochondria, Hrk, If the cell undergoes loss of attachment (anoikis), NOXA, PUMA and Bmf, The BH3 domain of Bmf facilitates binding to a hydrophobic groove on the surface of Bcl-2, The gene encoding Bmf maps to chromosome 15q14, and in hematopoietic tissues, are proapoptotic members of the Bcl-2 family, liver and kidney, the cytoskeleton is disrupted and Bmf is released from DLC2, where Bcl-2 (an anti-apoptotic family member) is sequestered, which include Blk, The BH3-only proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BMF_HUMAN, Bcl-2-modying factor, Bcl2 modying factor, Bmf, FLJ00065, Bcl 2 modying factor
Also known asBcl2 modifying factor Antibody
Other nameAnti-Bcl2 modifying factor
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Description Complex subunit associated factors are involved in hybridoma growth, Eosinohils, NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation, Aplha
Gene targetBcl2 modifying factor
Short name Fluor 594, Anti-Bcl2 modifying factor
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-B-cell CLL/lymphoma 2 modifying factor

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