Anti-Bcr (Tyr360) (Polyclonal), ALEXA Fluor 594

Anti-Bcr (Tyr360) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Price 516

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	Bcr Tyr360
Specificity	This antibody reacts specifically with Bcr (Tyr360)
Modification	Phosphorylation
Modification site	Tyr360
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic phosphopeptide derived from human Bcr around the phosphorylation site of Tyr360 [TT(p-Y)RM]
Gene ID	613
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Although the BCR-ABL fusion protein has been extensively studied, The chromosome 22 breakpoint for this translocation is located within the BCR gene, The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac, The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, Two transcript variants encoding different isoforms have been found for this gene, the function of the normal BCR gene product is not clear, the gene at the chromosome 9 breakpoint, which is often found in patients with chronic myelogenous leukemia, A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, BCR_HUMAN, Bcrphospho Y360, CML, P-Bcrphospho Y360, PHL, breakpoint cluster region, Bcr phospho Y360
Also known as	Bcr (Tyr360) Polyclonal Antibody
Other name	Anti-Bcr (Tyr360) Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	Bcr (Tyr360)
Short name	Anti-Bcr (Tyr360) (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-Bcr (Tyr360) (polyclonal)
Alternative technique	polyclonals

Anti-Bcr (Tyr360) (Polyclonal), ALEXA Fluor 594

Anti-Bcr (Tyr360) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

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