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Anti-BHLHB5 (Polyclonal), ALEXA Fluor 594

Anti-BHLHB5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBHLHB5
SpecificityThis antibody reacts specifically with BHLHB5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human BHLHB5
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information BETA 3 contains a putative DNA-binding domain, BETA 3 is a protein that is functionally similar to members of the Id family in that it can inhibit the binding of E47 homodimers as well as E47/Neuro D and E47/Myo D heterodimers to consensus DNA sequences , Class A proteins heterodimerize with class B proteins to activate transcription, Class A proteins include the ubiquitously expressed E-box binding factors E12/E47, Class B proteins such as Myo D, For instance, ITF2 and HEB (BETA 1 or HTF4), In contrast to members of the Id family, The Id family can therefore form heterodimers with the myogenic family, Working in opposition to these positively acting factors are a specialized group of proteins that function as dominant negative regulators, but the resulting complexes are transcriptionally inactive, myogenin and Neuro D (BETA 2) are transiently expressed and exhibit a more limited tissue distribution, the Id family of transcriptional repressors contains a HLH region required for dimerization but lacks a functional DNA-binding domain, Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CAGL85 Beta3 bHLHe22
Also known asBHLHB5 Polyclonal Antibody
Other nameAnti-BHLHB5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetBHLHB5
Short nameAnti-BHLHB5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-BHLHB5 (polyclonal)
Alternative techniquepolyclonals
Identity 11963
Gene BHLHE22
Long gene name basic helix-loop-helix family member e22
Synonyms gene TNRC20 BHLHB5
Synonyms gene name 5 basic helix-loop-helix family, class B, member e22 , trinucleotide repeat containing 20 basic helix-loop-helix domain containing
Locus 8q12, 3
Discovery year 2000-01-27
GenBank acession U80755
Entrez gene record 27319
Pubmed identfication 9225980 12213201 18557763
RefSeq identity NM_152414
Classification Basic helix-loop-helix proteins Trinucleotide repeat containing
Havana BLAST/BLAT OTTHUMG00000164386

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