Name : Anti-BHLHB5 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1843432953
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | BHLHB5 |
| Specificity | This antibody reacts specifically with BHLHB5 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human BHLHB5 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | BETA 3 contains a putative DNA-binding domain, BETA 3 is a protein that is functionally similar to members of the Id family in that it can inhibit the binding of E47 homodimers as well as E47/Neuro D and E47/Myo D heterodimers to consensus DNA sequences , Class A proteins heterodimerize with class B proteins to activate transcription, Class A proteins include the ubiquitously expressed E-box binding factors E12/E47, Class B proteins such as Myo D, For instance, ITF2 and HEB (BETA 1 or HTF4), In contrast to members of the Id family, The Id family can therefore form heterodimers with the myogenic family, Working in opposition to these positively acting factors are a specialized group of proteins that function as dominant negative regulators, but the resulting complexes are transcriptionally inactive, myogenin and Neuro D (BETA 2) are transiently expressed and exhibit a more limited tissue distribution, the Id family of transcriptional repressors contains a HLH region required for dimerization but lacks a functional DNA-binding domain, Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CAGL85 Beta3 bHLHe22 |
| Also known as | BHLHB5 Polyclonal Antibody |
| Other name | Anti-BHLHB5 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | BHLHB5 |
| Short name | Anti-BHLHB5 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-BHLHB5 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 11963 |
| Gene | BHLHE22 |
| Long gene name | basic helix-loop-helix family member e22 |
| Synonyms gene | TNRC20 BHLHB5 |
| Synonyms gene name | 5 basic helix-loop-helix family, class B, member e22 , trinucleotide repeat containing 20 basic helix-loop-helix domain containing |
| Locus | 8q12, 3 |
| Discovery year | 2000-01-27 |
| GenBank acession | U80755 |
| Entrez gene record | 27319 |
| Pubmed identfication | 9225980 12213201 18557763 |
| RefSeq identity | NM_152414 |
| Classification | Basic helix-loop-helix proteins Trinucleotide repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000164386 |