Filters

Anti-Bid (Ser61) (Polyclonal), ALEXA Fluor 594

Anti-Bid (Ser61) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBid Ser61
SpecificityThis antibody reacts specifically with Bid (Ser61)
ModificationPhosphorylation
Modification siteSer61
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from mouse Bid around the phosphorylation site of Ser61
Gene ID12122
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesMouse (Mus musculus)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas, Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, In animal model studies, Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway, Mutation in the SH3 domain can diminish the cytochrome c releasing activity, The cytochrome c releasing activity of Bid was antagonized by Bcl2, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor, which in turn induces cytochrome c release and mitochondrial damage, Bid
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms AltName: BH3-interacting domain death agonist p15, BH3 interacting domain death agonist, BH3-interacting domain death agonist, BH3-interacting domain death agonist p11, BH3-interacting domain death agonist p13, BID, p-Bid phospho S61, p11 BID, p13 BID, p22 BID, Bid phospho S61
Also known asBid (Ser61) Polyclonal Antibody
Other nameAnti-Bid (Ser61) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetBid (Ser61)
Short nameAnti-Bid (Ser61) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-BH3 interacting domain death a this GO nist (Ser61) (polyclonal)
Alternative techniquepolyclonals

Similar products

Subscribe to our Newsletter